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Updated: Apr 20, 2026

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Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
Published on: September 2, 2025
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Real-time computer-generated integral imaging and 3D image calibration for augmented reality surgical navigation.
Junchen Wang1, Hideyuki Suenaga2, Hongen Liao3
1Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Summary
This study introduces a new augmented reality (AR) device for precise 3D surgical navigation. The system achieves sub-millimeter accuracy for 3D image overlay, enhancing surgical guidance.
Area of Science:
- Medical Imaging
- Computer Graphics
- Augmented Reality
Background:
- Autostereoscopic 3D image overlay is crucial for augmented reality (AR) surgical navigation.
- Existing methods lack high geometric fidelity and quantitative evaluation of 3D image accuracy.
Purpose of the Study:
- To propose a novel AR device for high-fidelity 3D image surgical overlay.
- To develop a GPU-based integral imaging pipeline and an automatic calibration paradigm for accurate 3D display.
Main Methods:
- Implemented a graphics processing unit (GPU)-based computer-generated integral imaging pipeline for real-time 3D display.
- Developed an automatic closed-loop 3D image calibration paradigm for undistorted 3D image display.
- Integrated a 3D display, AR window, stereo camera, and workstation into a novel AR device.
Main Results:
- Achieved rendering speeds of 50-60 fps for surface models and 5-8 fps for large medical volumes at 2560x1600 resolution.
- Demonstrated sub-millimeter geometric accuracy for undistorted 3D images post-calibration.
- Phantom experiments showed satisfactory image registration and overlay accuracy, confirming system usability in simulated oral and maxillofacial surgery.
Conclusions:
- The proposed GPU-based pipeline and calibration paradigm enable accurate and real-time autostereoscopic 3D display for AR surgical navigation.
- The novel AR device offers high geometric fidelity and sub-millimeter accuracy, significantly improving surgical overlay capabilities.
- The system's performance and usability were validated through rendering benchmarks and surgical simulation experiments.

