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Neurulation

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...

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Related Experiment Video

Updated: Apr 20, 2026

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

Published on: April 14, 2017

Microcephaly

C G Woods¹, R Basto²

¹Cambridge Institute for Medical Research, Cambridge University, Addenbrookes Hospital, Cambridge, UK.

Current Biology : CB

|December 4, 2014

Summary

No abstract available in PubMed .

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