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Published on: October 20, 2023
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa. A new comprehensive review
1Department of Cardiology, Atatürk Pulmonary Disease and Thorax Surgery Research Hospital, Sanatoryum Street, 06280, Ankara, Turkey, ekremsahan@hotmail.com.
Abstract:
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is an infrequent but potentially life-threatening condition. Both transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) can detect P-MAIVF with sensitivity rates of 43 and 90 %, respectively. The typical finding of echocardiography is a pulsatile echo-free sac that expands in systole and collapses in diastole. Our review comprises 166 patients with P-MAIVF, including eight cases in our hospital and 158 cases from the literature. P-MAIVF is often associated with infection or surgical trauma. While it is likely to maintain an asymptomatic course, symptoms of shortness of breath, heart failure, valvular disease, chest pain, endocarditis, and cerebrovascular events are common clinical presentations. The recommended treatment is surgery. However, conservative therapy is an alternative approach for high-risk patients or when surgical treatment is refused. With the increasing incidence of cardiac surgery and infective endocarditis, a likely increment in the new diagnosis of pseudoaneurysm is expected.
Insights
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare but serious condition. Diagnosis relies on echocardiography, with surgery being the primary treatment, though conservative options exist.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Imaging
Background:
- Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is an uncommon yet critical cardiovascular pathology.
- It is frequently linked to prior cardiac surgery or infective endocarditis.
Purpose of the Study:
- To review the diagnostic modalities, clinical presentations, and management strategies for P-MAIVF.
- To analyze a cohort of 166 patients diagnosed with P-MAIVF.
Main Methods:
- A comprehensive literature review was conducted, supplemented by data from eight cases at the authors' institution.
- Diagnostic accuracy of transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) was assessed.
Main Results:
- Transesophageal echocardiography (TEE) demonstrated higher sensitivity (90%) compared to transthoracic echocardiography (TTE) (43%) in detecting P-MAIVF.
- Common presentations include heart failure, valvular disease, and cerebrovascular events; however, asymptomatic cases are frequent.
- Surgical intervention is the recommended treatment, with conservative management reserved for high-risk or non-compliant patients.
Conclusions:
- P-MAIVF diagnosis and management require careful consideration of imaging modalities and patient-specific factors.
- An anticipated increase in P-MAIVF diagnoses is expected due to rising rates of cardiac surgery and infective endocarditis.
Related Concept Videos
Mitral Stenosis I: Introduction
Aneurysm I: Introduction
Mitral Valve Prolapse I: Introduction
Mitral Regurgitation I: Introduction
Aneurysm III: Interprofessional Care
Mitral Valve Prolapse II: Assessment and Management

