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Updated: Apr 20, 2026

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Selective recognition of Glutamate based on fluorescence enhancement of graphene quantum dot
Morteza Hosseini1, Hossein Khabbaz1, Amin Shiralizadeh Dezfoli2
1Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran.
Abstract:
Graphene quantum dots (GQDs) have successfully been utilized as an efficient nano-sized fluorescence chemosensor to detect selectively Glutamate (Glu) in Tris-HCl buffer solution (pH=9). The fluorescence emission spectrum of graphene quantum dots was at about 430nm. The study showed that fluorescence intensity of the quantum dot gradually enhanced with increase in concentration of Glutamate and any change in fluorescence intensity was directly proportional to the concentration of Glutamate. Under optimum conditions, the linear range for the detection of Glutamate was 1.6×10(-7)M to 1.0×10(-5)M with a detection limit of 5.2×10(-8)M. The sensor showed high selectivity toward Glutamate in comparison with other amino acids.

