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Updated: Apr 20, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Depression in the U.S. household population, 2009-2012
Depression affects 7.6% of Americans, particularly females and older adults. Those below the poverty level face significantly higher risks and functional difficulties, with low treatment rates observed.
Area of Science:
- Public Health
- Epidemiology
- Mental Health Research
Background:
- Depression is a serious medical illness impacting mood, cognition, and physical health.
- It is linked to increased chronic disease, healthcare use, and functional impairment.
- Current treatment rates for depression remain low and often inadequate.
Purpose of the Study:
- To examine the prevalence of depression and depressive symptom severity in Americans aged 12 and over.
- To analyze depression rates by demographic characteristics, socioeconomic status, and functional difficulties.
- To assess the utilization of mental health services among individuals with severe depressive symptoms.
Main Methods:
- Utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted from 2009-2012.
- Employed a symptom-based questionnaire to assess depressive symptoms in the past two weeks.
- Categorized depression severity into severe, moderate, mild, or no symptoms based on the questionnaire responses.
Main Results:
- During 2009-2012, 7.6% of Americans aged 12+ experienced depression (moderate or severe symptoms).
- Prevalence was higher in females and adults aged 40-59. Individuals below the poverty level were nearly 2.5 times more likely to have depression.
- Nearly 43% of those with severe symptoms reported significant functional difficulties; 35% had recent mental health professional contact.
Conclusions:
- Depression is a significant public health concern with notable disparities in prevalence and impact.
- Socioeconomic status is a strong determinant of depression risk and associated functional impairment.
- Despite severe symptoms and functional difficulties, mental health service utilization remains a concern.
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