Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development

Thomas Volckaert1, Stijn P De Langhe

  • 1Department of Pediatrics, Division of Cell Biology, National Jewish Health, Denver, Colorado; The Inflammation Research Center, Unit of Molecular Signal Transduction in Inflammation, VIB, Technologiepark 927, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, 9052 Ghent, Belgium.

Summary

Mammalian lung development involves complex epithelial and mesenchymal cell communication. Wnt and FGF signaling pathways are key regulators, influencing both development and adult lung regeneration.

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