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Correlation of C-reactive protein and body mass index with diabetic retinopathy in Indian population
Dipayan Sen1, Sambuddha Ghosh1, Debesh Roy1
1Regional Institute of Ophthalmology and Department of Biochemistry, Medical College, 88 College Street, Kolkata 700073, India.
Background:
Association of C-reactive protein (CRP) and body mass index (BMI) with diabetic retinopathy (DR) has conflicting reports.
Method:
Sixty diabetes patients each with DR (Group A), no DR (Group B) and 60 healthy volunteers (control, group C) were studied. CRP was measured. BMI was calculated.
Result:
Significant difference in CRP was observed between groups A & B (p=0.000) and A & C (p=0.007). No significant difference in BMI was observed. Central macular thickness correlated positively with CRP and negatively with BMI.
Conclusion:
We observed strong association of CRP with DR and no significant relationship between DR and BMI.
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