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Coffee silverskin: a possible valuable cosmetic ingredient
Francisca Rodrigues1, Ana Palmeira-de-Oliveira, José das Neves
1Department of Chemical Sciences, Faculty of Pharmacy, REQUIMTE, University of Porto , Porto , Portugal .
Pharmaceutical Biology
|December 5, 2014
Summary
Coffee silverskin (CS) extracts are a safe, natural source of antioxidants with antimicrobial properties. These extracts show potential for cosmetic applications due to their beneficial effects and lack of cytotoxicity.
Area of Science:
- Cosmetic Science
- Natural Product Chemistry
- Dermatology
Background:
- Growing demand for natural ingredients in cosmetics.
- Coffee silverskin (CS) is a significant by-product of coffee processing.
- Potential of natural extracts as functional cosmetic ingredients.
Purpose of the Study:
- Evaluate coffee silverskin (CS) extracts for cosmetic applications.
- Assess antioxidant, antimicrobial, and cytotoxic properties of CS extracts.
- Investigate environmentally friendly extraction methods for CS.
Main Methods:
- Obtained aqueous, hydroalcoholic, and ethanolic CS extracts using an eco-friendly process.
- Quantified total phenolic and flavonoid content (TPC, TFC).
- Assessed antioxidant activity (DPPH, FRAP), antimicrobial activity (MIC), and cytotoxicity (MTS, LDH) on skin cells.
Main Results:
- CS extracts exhibited high TPC and TFC.
- Significant antioxidant activity was observed.
- Extracts demonstrated broad-spectrum antibacterial activity with varying MIC values.
- No cytotoxicity was observed in fibroblast and keratinocyte cell lines.
Conclusions:
- Coffee silverskin is a safe and valuable source of natural antioxidants.
- CS extracts possess potent antifungal and antibacterial activities.
- The non-cytotoxic nature of CS extracts supports their use in cosmetic formulations.
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