Related Experiment Video
Updated: Apr 20, 2026

10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
2.1K
Post-traumatic optic neuropathy: our surgical and medical protocol
E Emanuelli1, M Bignami2, E Digilio2
1Department of Otorhinolaryngology and Otology Surgery of the University of Padova, via Giustiniani 2, Padua, Italy. enzoemanuelli@libero.it.
Summary
Post-traumatic optic neuropathy (TON) treatment remains unclear. A combined approach of early steroid therapy followed by endoscopic optic nerve decompression improved visual acuity in 65% of patients with minimal complications.
Area of Science:
- Ophthalmology
- Neurosurgery
- Trauma Care
Background:
- Post-traumatic optic neuropathy (TON) is a severe injury causing vision loss.
- No definitive treatment strategy currently exists for TON.
- Road traffic accidents are the most common cause of TON.
Purpose of the Study:
- To evaluate the efficacy and safety of a combined medical and surgical treatment protocol for TON.
- To determine the optimal timing for intervention in TON management.
Main Methods:
- Retrospective review of 26 patients treated between 2002 and 2013.
- All patients received initial systemic corticosteroid therapy.
- Surgical treatment involved endonasal endoscopic decompression of the optic nerve.
Main Results:
- Visual acuity improved in 65% of patients.
- Surgery performed closer to the injury time yielded better results.
- No intra- or post-operative complications were reported.
Conclusions:
- A protocol of early intravenous steroid treatment followed by endoscopic optic nerve decompression offers a favorable risk-benefit ratio.
- Prompt surgical intervention, ideally within 12-24 hours of medical therapy initiation, is crucial for visual recovery.
- Further evidence-based research is needed to establish a gold standard for TON treatment.
Related Concept Videos
Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment
1.7K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.7K
Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K

