Primary percutaneous coronary intervention ameliorates complete atrioventricular block complicating acute inferior

Su Nam Lee1, You-Mi Hwang1, Gee-Hee Kim1

  • 1Department of Internal Medicine, St Vincent's Hospital, The Catholic University of Korea, Suwon, South Korea.

Insights

Primary percutaneous coronary intervention (PCI) effectively treats complete atrioventricular block (CAVB) in acute inferior ST-elevation myocardial infarction (STEMI). This approach leads to CAVB reversal and comparable major adverse cardiac events, making it the preferred reperfusion therapy.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Acute Myocardial Infarction

Background:

  • Complete atrioventricular block (CAVB) in acute inferior ST-elevation myocardial infarction (STEMI) historically correlates with adverse clinical outcomes.
  • Noninvasive treatments for CAVB in STEMI have shown limited success.

Purpose of the Study:

  • To evaluate the efficacy of primary percutaneous coronary intervention (PCI) in patients experiencing CAVB during acute inferior STEMI.
  • To compare clinical outcomes between patients with and without CAVB undergoing primary PCI.

Main Methods:

  • A single-center study included 138 patients with inferior STEMI, with 27 diagnosed with CAVB.
  • All patients underwent primary PCI; clinical characteristics, procedural details, and outcomes were analyzed.
  • Comparison was made between patients with CAVB and those without.

Main Results:

  • Patients with CAVB were more prone to cardiogenic shock, often due to right coronary artery occlusion.
  • Primary PCI successfully reversed CAVB in all affected patients.
  • Post-PCI, peak creatinine phosphokinase, ejection fraction, and in-hospital mortality were similar between groups.
  • Major adverse cardiac events at 318-day follow-up did not significantly differ between patients with and without CAVB.

Conclusions:

  • Primary PCI is a highly effective reperfusion strategy for acute inferior STEMI complicated by CAVB.
  • This intervention ameliorates CAVB and is associated with acceptable rates of major adverse cardiac events.
  • Primary PCI should be considered the preferred treatment for CAVB complicating acute inferior myocardial infarction.
Abstract

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