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Updated: Apr 20, 2026

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Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
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Profound amnesia after temporal lobectomy: an autoimmune process resembling patient h.m.?
Michael Bonello1, Andrew J Larner1, Anthony G Marson1
1Walton Centre for Neurology and Neurosurgery, Liverpool, UK.
Case Reports in Neurology
|December 5, 2014
Summary
A patient experienced cognitive decline after epilepsy surgery. Inflammation and anti-glutamic acid decarboxylase (GAD) antibodies indicated limbic encephalitis, not structural damage.
Area of Science:
- Neurology
- Immunology
- Neuropsychology
Background:
- Refractory epilepsy often necessitates surgical intervention, such as temporal lobectomy.
- Cognitive decline and amnesia can occur post-surgery, with differential diagnoses including structural pathology and inflammatory conditions.

