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Updated: Apr 20, 2026

Preparation of Agar Bead Embedded Mycobacterium abscessus to Inoculate Immunocompetent Mice Intratracheally
Published on: April 25, 2025
Mycobacterium abscessus - to treat or not to treat
Yong-Kek Pang1, Yun-Fong Ngeow2, Yan-Ling Wong2
1Department of Medicine, Faculty of Medicine, University of Malaya Medical Centre, University of Malaya Kuala Lumpur, Malaysia.
Abstract:
A patient with Mycobacterium abscessus lung disease was mistaken to have pulmonary tuberculosis with airway colonization by the non-tuberculous mycobacterium. Appropriate antibiotics were only given when the patient's signs and symptoms worsened while on anti-tuberculosis therapy. Despite treatment with a combination of antibiotics showing in vitro susceptibility, the pathogen persisted in the respiratory secretions for longer than 6 months and the patient suffered a spontaneous pneumothorax 14 months into treatment. This case illustrates the chronic course of M. abscessus lung infection, the tendency for flare-ups, the inadequacy of current treatment regimens, and the necessity for prolonged patient follow-up.
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