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High-risk pregnancy and the rheumatologist
May Ching Soh1, Catherine Nelson-Piercy2
1Division of Women's Health, Women's Health Academic Centre, King's College London, King's Health Partners, London, UK.
Rheumatology (Oxford, England)
|December 6, 2014
Summary
Most women with rheumatic diseases can have successful pregnancies with careful planning. This review covers high-risk pregnancies, complications, and treatments for conditions like SLE and RA during pregnancy and breastfeeding.
Area of Science:
- Rheumatology
- Obstetrics
- Immunology
Background:
- Biologic therapies improve rheumatic disease control, enabling more women to attempt pregnancy.
- Rheumatologists play a crucial role in managing rheumatic diseases during pregnancy.
Purpose of the Study:
- To review high-risk pregnancies in women with rheumatic diseases.
- To discuss maternal and fetal complications, treatments, and long-term outcomes.
- To address controversies surrounding biologic use in pregnancy.
Main Methods:
- Literature review focusing on high-risk pregnancies and specific rheumatic conditions.
- Discussion of evidence and controversies regarding treatment options.
- Emphasis on the multidisciplinary team approach.
Main Results:
- Most women with rheumatic diseases can achieve successful pregnancies with proper management.
- Specific risks and complications associated with conditions like SLE, RA, and vasculitides are detailed.
- Evidence and controversies regarding biologic use during pregnancy and breastfeeding are presented.
Conclusions:
- Careful pregnancy planning and multidisciplinary care are essential for successful outcomes.
- Rheumatologists are vital in guiding management throughout pregnancy and postpartum.
- Further research is needed to clarify optimal management strategies, especially concerning biologics.
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