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Left Bundle Branch Block in Acute Cardiac Events: Insights From a 23-Year Registry

Fahad Alkindi1, Ayman El-Menyar2, Jassim Al-Suwaidi1

  • 1Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.

Angiology
|December 6, 2014
PubMed

Insights

Left bundle branch block (LBBB) patients are older, female, and have more comorbidities. Congestive heart failure (CHF) is the main cause of admission and the only predictor of mortality in LBBB patients.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Clinical Research

Background:

  • Left bundle branch block (LBBB) is a common finding in patients with cardiac conditions.
  • Understanding the characteristics and outcomes of LBBB patients is crucial for effective management.

Purpose of the Study:

  • To evaluate the demographics, clinical presentation, and final diagnosis of hospitalized patients with acute cardiac events and LBBB.
  • To identify predictors of in-hospital mortality in patients with LBBB.

Main Methods:

  • Retrospective analysis of 50,992 patients hospitalized between 1991 and 2013.
  • Comparison of demographic and clinical data between patients with and without LBBB.
  • Multivariate analysis to determine predictors of in-hospital mortality.

Main Results:

  • 1.5% of patients had LBBB; these patients were older, more frequently female, diabetic, and had hypertension and chronic kidney failure (CKF).
  • Dyspnea and dizziness were more common in LBBB patients. Congestive heart failure (CHF) was the most frequent admission diagnosis (54.2%), followed by ST-elevation myocardial infarction (STEMI; 13.3%).
  • CKF and LBBB were predictors of in-hospital mortality in the overall population. In LBBB patients, only CKF predicted mortality (OR: 2.93). CHF was the final diagnosis in most LBBB cases.

Conclusions:

  • Patients with LBBB admitted for acute cardiac events have distinct demographic and comorbidity profiles.
  • Chronic kidney failure is a significant predictor of in-hospital mortality in patients with LBBB.
  • Congestive heart failure remains the primary diagnosis and driver of outcomes in LBBB patients.

Keywords:
Qatarheart failureleft bundle branch blockmyocardial infarction

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