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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
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Bacteriology of inverted papilloma.
Rhinology
|December 6, 2014
Summary
Bacterial analysis of inverted papilloma (IP) in the nasal cavity shows similar microbes to chronic rhinosinusitis (CRS). No differences were found between primary and recurrent IP, suggesting IP doesn't stem from specific microbial exposure.
Area of Science:
- Otolaryngology
- Microbiology
- Pathology
Background:
- Inverted papilloma (IP) is a benign nasal and paranasal sinus lesion.
- The exact cause of IP is currently unknown.
Purpose of the Study:
- To compare sinonasal bacteriology in IP patients with chronic rhinosinusitis (CRS) patients.
- To investigate bacteriological differences between primary and recurrent IP.
Main Methods:
- Retrospective review of 26 IP cases at a tertiary referral center.
- Comparison of intraoperative microbiology from primary and revision IP resections.
- Comparison with published microbiology data from CRS patients.
Main Results:
- Most common isolates in IP: coagulase-negative Staphylococcus, Propionibacterium, Staphylococcus aureus, Streptococcus.
- Bacteriology trends in IP were similar to those reported for CRS.
- No significant bacteriological differences were observed between primary and recurrent IP.
Conclusions:
- The most common bacterial isolates in IP are similar to those found in CRS.
- No difference in bacteriology was found between primary and recurrent IP.
- Findings suggest IP is not caused by specific sinonasal microbial exposure.
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