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Monoclonal antibodies to type D retrovirus (SRV-2)
C C Tsai1, C C Tsai, J M Sligh
1Department of Pathology, St. Louis University School of Medicine, MO.
Journal of Medical Primatology
|January 1, 1989
Abstract:
Monoclonal antibodies (MoAbs) to the major gag core protein p27 and a viral protein p44 of type D retrovirus (SRV-2) were produced and used in the detection of SRV-2 antigens in infected Raji cells and in tissues from macaques with simian acquired immunodeficiency syndrome (SAIDS) and retroperitoneal fibromatosis (RF). Anti-p44 MoAb showed inhibition of syncytium formation by both SRV-1- and SRV-2-infected Raji cells.