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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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Rupture after endovascular abdominal aortic aneurysm repair: a multicenter study
Constantine N Antonopoulos1, John D Kakisis2, Triantafillos G Giannakopoulos2
1Department of Vascular Surgery, University General Hospital "Attikon", Athens, Greece kostas.antonopoulos@gmail.com.
Vascular and Endovascular Surgery
|December 7, 2014
Summary
Rupture after endovascular aortic repair (EVAR) is increasing. Type Ia endoleak and endograft migration are common complications, with low follow-up compliance contributing to poor outcomes.
Area of Science:
- Vascular Surgery
- Endovascular Repair
- Aortic Aneurysm Management
Background:
- Ruptured abdominal aortic aneurysms (rAAAs) pose significant mortality risks.
- Endovascular aortic repair (EVAR) is a common treatment for AAAs.
- Rupture after EVAR (rAAAevar) represents a challenging clinical scenario.
Purpose of the Study:
- To investigate the incidence, causes, and outcomes of rAAAevar.
- To analyze trends in rAAAevar over time.
- To identify factors associated with in-hospital mortality in rAAAevar patients.
Main Methods:
- Retrospective analysis of 22 patients with rAAAevar treated at 7 Greek referral hospitals (January 2006 - April 2012).
- Evaluation of endoleak types, endograft migration, and follow-up compliance.
- Comparison of mortality rates between secondary EVAR and open surgical repair.
Main Results:
- rAAAevar incidence increased significantly from 1.3% in 2007 to 18.2% in 2012.
- Type Ia endoleak (72.7%) and endograft migration (50%) were the most frequent complications.
- In-hospital mortality was 36.4%, with significantly lower rates for secondary EVAR (9.1%) versus open repair (63.6%).
- Pre-rupture follow-up compliance was low (31.8%).
Conclusions:
- Rupture after EVAR is an emerging clinical problem with increasing frequency.
- Type I endoleak and endograft migration are primary contributors to rAAAevar.
- Improved surveillance and timely reintervention are crucial for reducing mortality in rAAAevar patients.
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