Metastatic gallbladder adenosquamous carcinoma to the skin†
Renato Micelli Lupinacci1, André Santana2, André Roncon Dias3
1Service de chirurgie digestive, viscérale et endocrinienne, Groupe Hospitalier Diaconesses Croix-Saint-Simon, Paris, France Department of Gastroenterology, University of São Paulo Medical School, São Paulo, Brazil rmlupinacci@gmail.com.
Abstract:
Cutaneous metastasis (CM) is an uncommon manifestation of visceral malignancies. Adenosquamous carcinoma of the gallbladder is a rare variation in gallbladder carcinoma (GBC), associated with worse prognosis. We present the case of a 56-year-old woman who presented with an inflamed lump on her abdominal wall. Computed tomography (CT) revealed a large mass from the gallbladder invading the abdominal wall. She underwent liver resection with regional lymphadenectomy. Pathology analysis revealed a 12-cm pT3N0 GBC. Hospital discharge occurred at post-operative Day 20. She recurred and died 10 months after surgery. Survival after the diagnosis of CM is dismal. The present case was a diagnostic trap. First, the patient's skin lesion presented as a cutaneous abscess and biopsy revealed a squamous cell cancer. A CT scan suggested a continuous mass involving the abdominal wall. CM was only suspected during surgery when no continuity between the tumour and the abdominal wall was identified.
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