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Methods and challenges in quantitative imaging biomarker development
Richard G Abramson1, Kirsteen R Burton2, John-Paul J Yu3
1Department of Radiology and Radiological Sciences, Vanderbilt University, 1161 21st Avenue South, CCC-1121 MCN, Nashville, TN 37232-2675.
Abstract:
Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.
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