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A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Noninvasive carotid duplex study may be used as predictor test for ischaemic heart disease
N Fatema1, M S Haque, M A Siddique
1Dr Nilufar Fatema, Consultant, Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh.
Insights
Carotid atherosclerosis, indicated by increased intima-media thickness (IMT), is common in patients with ischemic heart disease (IHD). Non-invasive carotid duplex ultrasound can help predict IHD.
Area of Science:
- Cardiology
- Vascular Ultrasound
- Diagnostic Imaging
Background:
- Ischemic heart disease (IHD) poses a significant global health burden.
- Carotid atherosclerosis is a known risk factor and marker for systemic atherosclerosis.
- Early detection of carotid atherosclerosis may aid in IHD risk stratification.
Purpose of the Study:
- To investigate the prevalence of carotid atherosclerosis in patients with clinically diagnosed IHD.
- To assess the correlation between carotid intima-media thickness (IMT) and IHD.
- To evaluate the utility of non-invasive carotid duplex ultrasound in predicting IHD.
Main Methods:
- Prospective observational study involving 150 in-hospital patients with diagnosed IHD.
- High-resolution B-mode carotid ultrasound was performed by a single operator.
- Intima-media thickness (IMT) measurements and atherosclerotic plaque detection were analyzed.
Main Results:
- The mean IMT was 0.96±0.21mm, exceeding the normal threshold (≤0.8mm) in 85% of IHD patients.
- Atherosclerotic plaque was detected in approximately 77% of the study cohort.
- A significant positive correlation was observed between carotid atherosclerosis (IMT) and the presence of IHD.
Conclusions:
- Carotid atherosclerosis is highly prevalent in patients with IHD.
- Elevated carotid IMT and plaque presence are associated with IHD.
- Non-invasive carotid duplex ultrasound is a potentially valuable tool for predicting IHD.
Abstract:
A prospective observational study was carried out to detect carotid atherosclerosis using high resolution B-Mode in 150 in-hospital patients with clinically diagnosed ischemic heart disease in various forms in the department of Cardiology, University Cardiac Center, BSMMU, Bangladesh. The duration of study was from April 2006 to December 2008. Carotid Ultrasound evaluation was performed in 150 patients diagnosed as Ischemic Heart Disease by single operator (NF). Mean age of the patients was 53.62±10.92 with, male to female ratio of 9.5:0.5. Mean IMT was 0.96±0.21mm in 85% of the patient of clinically diagnosed IHD, which was higher than the normal (normal IMT ≤0.8mm). Among them, about 77% had atherosclerotic plaque. A significant correlation between Carotid atherosclerosis determined by IMT and Ischemic Heart Disease (IHD) was found. Non invasive carotid duplex study might be useful for predicting ischaemic heart disease.
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