Related Experiment Video

Updated: Jun 20, 2026

A Tetracycline-regulated Cell Line Produces High-titer Lentiviral Vectors that Specifically Target Dendritic Cells
16:04

A Tetracycline-regulated Cell Line Produces High-titer Lentiviral Vectors that Specifically Target Dendritic Cells

Published on: June 19, 2013

DCVax®-L--developed by Northwest Biotherapeutics

Stavros Polyzoidis1, Keyoumars Ashkan

  • 1a Department of Neurosurgery; King's College Hospital; King's College ; London , UK.

Human Vaccines & Immunotherapeutics
|December 9, 2014
PubMed

Keywords:
BBB, blood brain barrierCNS, central nervous systemCTL, cytotoxic T-lymphocyteDC, dendritic cellDCVax®-LDTH, delayed tissue hypersensitivityEORTC, European Organization for Research and Treatment of CancerFDA, Food and Drug AdministrationGBM, glioblastoma multiformeGM-CSF, granulocyte-macrophage colony-stimulating factorHGG, high-grade gliomaIL-4, interleukin-4IMP, investigational medicinal productMHRA, Medicines and Healthcare products Regulatory AgencyMRI, magnetic resonance imagingND, newly diagnosedNIHR, National Institute for Health ResearchNWBT, Northwest Biotherapeutics Inc.OS, overall survivalPEI, Paul-Ehrlich-InstitutePFS, progression-free survivalTAAs, tumor-associated antigensUCLA, University of California, Los Angeles, U.S.A., United States of Americadendritic cellsglioblastoma multiformeimmunotherapyoverall survivalside effectsvaccine

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