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The novel species Streptococcus tigurinus and its association with oral infection
Andrea Zbinden1, Nagihan Bostanci, Georgios N Belibasakis
1a Institute of Medical Virology; University of Zurich ; Zurich , Switzerland.
Abstract:
Streptococcus tigurinus is a novel species of viridans streptococci, shown to cause severe invasive infections such as infective endocarditis, spondylodiscitis and meningitis. S. tigurinus belongs to the Streptococcus mitis group and is most closely related to Streptococcus mitis, Streptococcus oralis, Streptococcus pneumoniae, Streptococcus pseudopneumoniae and Streptococcus infantis. The presence of S. tigurinus in the human oral cavity has been documented, including in patients with periodontal disease. This review addresses the available scientific knowledge on S. tigurinus and its association with closely related streptococci, and discusses its putative involvement in common oral infections. While there is as yet no strong evidence on the involvement of S. tigurinus with oral infections, its presence in the oral cavity and its association with endocarditis warrants special attention for a link between oral and systemic infection.
Insights
Streptococcus tigurinus, a novel bacterium, can cause severe infections. Its presence in the mouth, even with periodontal disease, suggests a potential link between oral health and systemic Streptococcus tigurinus infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Oral Health
Background:
- Streptococcus tigurinus is a newly identified species within the viridans streptococci group.
- It is closely related to other bacteria in the Streptococcus mitis group, including Streptococcus pneumoniae.
- This bacterium has been detected in the human oral cavity, particularly in individuals with periodontal disease.
Purpose of the Study:
- To review current scientific knowledge on Streptococcus tigurinus.
- To explore its relationship with closely related streptococcal species.
- To discuss the potential role of Streptococcus tigurinus in oral infections.
Main Methods:
- Literature review of existing scientific studies on Streptococcus tigurinus.
- Comparative analysis of Streptococcus tigurinus with related species in the Streptococcus mitis group.
- Assessment of evidence linking Streptococcus tigurinus to oral and systemic infections.
Main Results:
- Streptococcus tigurinus is associated with severe invasive infections like endocarditis, spondylodiscitis, and meningitis.
- While found in the oral cavity, direct strong evidence linking it to common oral infections is currently lacking.
- Its association with endocarditis highlights a potential connection between oral bacteria and systemic disease.
Conclusions:
- Streptococcus tigurinus represents a significant pathogen capable of causing severe invasive diseases.
- Further research is needed to fully understand the role of Streptococcus tigurinus in oral health and its contribution to systemic infections.
- The presence of Streptococcus tigurinus in the oral cavity warrants attention due to its association with serious infections such as endocarditis.
Related Concept Videos
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Etiology
Three primary contributing factors have been identified.
Development of the Oral Microbiota
Microbiota of the Respiratory Tract
Colonisation of Pathogens

