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Updated: Apr 19, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
A clinical and statistical survey of cutaneous changes in the first 120 hours of life
Dinkar J Sadana1, Yugal K Sharma1, Nitin D Chaudhari1
1Department of Dermatology, Leprology and Venereology, Dr. D.Y. Patil Medical College, Pimpri, Pune, Maharashtra, India.
Insights
Neonatal skin conditions like desquamation and Mongolian spots are common and linked to maternal and infant factors. Further research in neonatal dermatology is needed to confirm these findings.
Area of Science:
- Neonatal Dermatology
- Pediatric Dermatology
- Cutaneous Manifestations in Newborns
Background:
- Neonatal skin conditions range from minor to severe, causing parental stress.
- Lack of specialized pediatric dermatology clinics often leads to fragmented care between pediatricians and dermatologists.
Purpose of the Study:
- To document neonatal cutaneous changes within the first five days of life.
- To statistically correlate observed skin changes with maternal and neonatal factors.
Main Methods:
- Descriptive, cross-sectional study of 300 neonates with cutaneous changes.
- Detailed dermatological examination and statistical analysis using the Chi-square test (P < 0.05).
Main Results:
- Superficial cutaneous desquamation (SCD), Mongolian spots (MS), and erythema toxicum neonatorum (ETN) were most common.
- SCD, MS, ETN, milia, and icterus showed significant correlation with maternal and neonatal factors.
- Gestational age, maternal illness, birth weight, parity, sex, and delivery mode were significant factors.
Conclusions:
- Eight neonatal skin changes correlated significantly with maternal and neonatal factors.
- Further extensive studies are required to validate these unique statistical correlations in neonatal dermatology.
Background:
The spectrum of dermatological manifestations during neonatal period varies from transient self-limiting conditions to serious dermatoses; the latter, fortunately few, are disproportionately stressful to the parents, who due to lack of specialized pediatric dermatology clinics frequently get tossed between a dermatologist and a pediatrician.
Objectives:
This study was formulated to record cutaneous changes over the first five postnatal days of life and to statistically correlate those changes occurring in ≥ 11 neonates with three (parity, associated illnesses, and mode of delivery) maternal and three (sex, birth weight, and gestational age) neonatal factors.
Methods:
This descriptive, cross-sectional study at a tertiary care hospital entailed recording detailed dermatological examination of 300 neonates having some (physiological and/or pathological) cutaneous changes and their statistical evaluation using the Chi-square test and significance (P < 0.05) as above.
Results:
Superficial cutaneous desquamation (SCD), Mongolian spots (MS), and erythema toxicum neonatorum (ETN) were the first three common changes among a total of 15 conditions observed overall; these three, as also milia and icterus, revealed statistical significance with both maternal as well as neonatal factors. Lanugo and napkin dermatitis (ND) were statistically significant with respect to two neonatal factors and cradle cap (CC), a single maternal factor. Gestational age was of statistical significance regarding five cutaneous changes, associated maternal illness during pregnancy regarding four, birth weight as well as parity regarding three each, and sex of the neonate as well as mode of delivery regarding two each.
Conclusion:
Despite observing a statistically significant correlation of eight cutaneous changes with three maternal and/or three neonatal factors, more extensive studies in neonatal dermatology are required for validation of these unique statistical correlations.
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