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Margins in skin excision biopsies: principles and guidelines
Richa Ranjan1, Lavleen Singh1, Sudheer K Arava1
1Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Indian Journal of Dermatology
|December 9, 2014
Summary
This review details skin biopsy techniques for diagnosing lesions and assessing surgical margins. Accurate margin assessment is crucial for predicting prognosis in malignant skin conditions.
Area of Science:
- Dermatopathology
- Surgical Pathology
- Oncology
Background:
- Skin biopsies are essential for clinical diagnosis, lesion removal, and evaluating excised tissue margins.
- Surgical margins, the edges of removed tissue, are critical in oncology.
- Tumor involvement at surgical margins is a key prognostic indicator for malignant lesions.
Purpose of the Study:
- To review the grossing techniques for skin biopsy specimens.
- To emphasize methods for reporting excision biopsy margins.
- To provide insights into accurate margin assessment in dermatopathology.
Main Methods:
- Review of grossing procedures for skin biopsies.
- Analysis of techniques for margin identification and evaluation.
- Discussion of reporting standards for excision biopsy margins.
Main Results:
- Grossing techniques directly impact the accuracy of margin assessment.
- Standardized reporting of margins improves prognostic accuracy.
- Clear margin definition is vital for patient management.
Conclusions:
- Proper grossing and reporting of skin biopsy margins are fundamental in surgical pathology.
- Accurate margin evaluation aids in determining the need for further treatment.
- This review highlights best practices for assessing skin excision margins.

