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Aquagenic syringeal acrokeratoderma
1Department of Dermatology, Sifa University, Basmane, Izmir, Turkey.
Indian Journal of Dermatology
|December 9, 2014
Summary
Aquagenic syringeal acrokeratoderma causes temporary hand wrinkling and pain after water exposure. A case study suggests spironolactone withdrawal may trigger these symptoms in women with polycystic ovary syndrome.
Area of Science:
- Dermatology
- Endocrinology
Background:
- Aquagenic syringeal acrokeratoderma is a rare palmoplantar condition characterized by transient, water-induced skin changes.
- Symptoms include tingling, pain, and distinctive wrinkling and papules on the hands and feet.
Purpose of the Study:
- To report a case of aquagenic syringeal acrokeratoderma in a patient with polycystic ovary syndrome.
- To explore a potential association between spironolactone withdrawal and the development of these symptoms.
Main Methods:
- Case report of a 21-year-old woman.
- Clinical observation of symptoms following spironolactone use and withdrawal for polycystic ovary syndrome.
Main Results:
- The patient presented with clinical features consistent with aquagenic syringeal acrokeratoderma.
- Symptoms appeared two weeks after discontinuing spironolactone therapy.
Conclusions:
- Spironolactone withdrawal may be a potential trigger for aquagenic syringeal acrokeratoderma in susceptible individuals.
- Further research is needed to confirm this association and understand the underlying mechanisms.
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