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Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro
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An innocent giant.

Lakhan Singh Solanki1, Mandeep Dhingra1, Gunjan Raghubanshi2

  • 1Department of Dermatology, Government Medical College and Hospital, Sector-32, Chandigarh, India.

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Summary
This summary is machine-generated.

Giant cutaneous horns, a skin protrusion of cornified material, can occur in young individuals. This case highlights a giant horn on a 24-year-old female

Keywords:
Cutaneous horngiant hornseborrheic keratosis

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • A cutaneous horn (cornu cutaneum) is a clinical presentation of a skin protrusion composed of keratin.
  • It can be associated with various underlying skin lesions, ranging from benign to malignant.

Purpose of the Study:

  • To report a rare case of a giant cutaneous horn in a young patient.
  • To emphasize that giant cutaneous horns can arise from benign lesions like seborrheic keratosis.
  • To highlight that these horns can occur in non-sun-exposed areas and are not always indicative of malignancy.

Main Methods:

  • Case presentation of a 24-year-old female with a giant cutaneous horn.
  • Clinical and histopathological evaluation of the lesion and its base.

Main Results:

  • A giant cutaneous horn was identified in a 24-year-old female.
  • The horn originated from a seborrheic keratosis on the leg.
  • The underlying lesion was benign, with no evidence of malignancy.

Conclusions:

  • Giant cutaneous horns can occur in young individuals.
  • Seborrheic keratosis is a possible underlying cause for giant cutaneous horns.
  • Location (including photoprotected areas) and age do not exclude benign etiology.