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An intravascular lymphoma with extravascular tendencies
Cody A Thomas1, Joseph M Guileyardo1, John R Krause1
1Department of Pathology, Baylor University Medical Center at Dallas and the Charles A. Sammons Cancer Center, Dallas, Texas.
Proceedings (Baylor University. Medical Center)
|December 9, 2014
Summary
Intravascular large B-cell lymphoma (IVL) is a rare cancer. This case highlights IVL with unusual spread beyond blood vessels into organs.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Intravascular large B-cell lymphoma (IVL) is a rare hematologic malignancy.
- It is defined by neoplastic lymphocytes proliferating within blood vessels.
Observation:
- A 69-year-old woman presented with widespread IVL.
- The lymphoma showed involvement within blood vessels and also extended into lymph nodes, liver, bladder, and adrenal gland.
Findings:
- This case demonstrates IVL with concurrent extravascular disease.
- The unique presentation challenges the typical understanding of IVL's exclusive intravascular localization.
Implications:
- Understanding IVL's varied presentations is crucial for diagnosis and treatment.
- This case broadens the pathological spectrum of intravascular large B-cell lymphoma.
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