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Updated: Apr 19, 2026

Method of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program
Published on: February 25, 2015
Single site cannulation veno-venous extracorporeal lung support during pulmonary resection in patients with severely
Bassam Redwan1, Michael Semik, Nicolas Dickgreber
1From the *Department of Thoracic Surgery and Lung Support, Klinikum Ibbenbueren, Ibbenbueren, Germany; †Department of Respirology, Thoracic Oncology and Respiratory Therapy, Mathias-Spital Rheine, Rheine, Germany; and ‡Department of Anesthesiology and Intensive Care Medicine, Klinikum Ibbenbueren, Ibbenbueren, Germany.
Abstract:
The intraoperative application of extracorporeal lung support devices during thoracic surgical procedures represents a modern concept with promising results. So far, pumpless extracorporeal interventional lung assist and veno-venous or veno-arterial extracorporeal membrane oxygenation via dual cannulation were utilized for complete or partial lung support throughout the surgical procedure. We report the initial intraoperative application of low-flow singular double-lumen veno-venous-extracorporeal membrane oxygenation for extracorporeal lung support during lung resections in patients with severely impaired preoperative pulmonary function. In our hands, this novel concept contributed to the safe performance of complex surgery in pulmonary compromised patients avoiding the possible complications of other forms of extracorporeal support.

