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Epigenetic reprogramming by somatic cell nuclear transfer: questions and potential solutions

Ji Huili1, Lu Haosheng2, Pan Dengke3

  • 1State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Animal Science and Technology, Guangxi University, Nanning 530004, China; Key Laboratory of Farm Animal Genetic Resources and Germplasm Innovation, Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;

Yi Chuan = Hereditas
|December 10, 2014
PubMed
Summary

Somatic cell nuclear transfer (SCNT) efficiency is limited by incomplete epigenetic reprogramming. This review highlights strategies to correct these errors, aiming to improve cloned animal development and applications.

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