[Influence of sampling satisfaction using endometrial sampling device and related factors for pathology diagnostic...

To observe the satisfaction of obtaining endometrial tissue in using endometrial sampling device and explore the influence for pathology diagnostic accordance rate, and to discuss the problem needs to focus in obtaining endometrial tissue with endometrial sampling device for endometrial cancer and precancerous lesion screening.

Totally 204 cases using endometrial sampling device with the subsequent diagnostic curettage, hysteroscopy, or hysterectomy were collected. A comparison of pathological diagnosis between two methods was made. The relationship among specimen quantity, proficiency, pathological types and diagnostic accordance rate were analyzed.

The diagnostic accordance rate of endometrial cancer and precancerous lesion of two methods was 67% (20/30). 92.2% (188/204) cases successfully got the endometrial glands, 77.0% (157/204) cases got ≥ 5 specimens of glands and 62.3% (127/204) cases got ≥ 10 specimens of glands. When obtaining ≥ 5 but < 10 endometrial glands, the diagnostic accordance rate was 76.7% (23/30); however, obtaining ≥ 10 endometrial glands, the diagnostic accordance rate was 92.9% (118/127). The degree of specimen satisfaction of the first phase was lower than the second phase.

Obtaining ≥ 5 endometrial glands in using endometrial sampling device could satisfy the requirement of the basic pathological diagnosis. The proficiency of sampling and the pathological types could influence the degree of specimen satisfaction, and then influence the diagnostic accordance rate.