Related Experiment Video

Updated: Apr 19, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

24.9K

Hepatitis C virus infection among hemodialysis patients in Asia: a meta-analysis

Y-B Liu1, J-Z Xie, C-J Zhong

  • 1Centre of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China. kailiu2013@hotmail.com.

European Review for Medical and Pharmacological Sciences
|December 10, 2014
PubMed

Insights

Hepatitis C virus (HCV) infection is prevalent in Asian hemodialysis patients, affecting 31% overall. Long-term dialysis and blood transfusions increase infection risk, necessitating enhanced preventive measures.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • Patients undergoing hemodialysis are at increased risk of infections.
  • Previous studies suggest a correlation between longer hemodialysis duration and higher infection rates.

Purpose of the Study:

  • To determine the prevalence of Hepatitis C Virus (HCV) infection in Asian hemodialysis patients.
  • To identify risk factors associated with HCV infection in this population.

Main Methods:

  • A systematic meta-analysis was conducted, reviewing Embase and PubMed databases.
  • Cross-sectional, retrospective, and prospective cohort studies published up to September 2013 were included.
  • Pooled analysis of prevalence rates and risk ratios (RR) with 95% confidence intervals (CI) was performed.

Main Results:

  • The overall prevalence of HCV infection among Asian hemodialysis patients was 31% (95% CI: 0.24-0.38).
  • Men had a higher prevalence (28%) than women (23%), with males being more vulnerable (RR = 1.24).
  • Long-term hemodialysis (RR = 0.55) and blood transfusion (RR = 0.82) were associated with increased HCV infection risk.

Conclusions:

  • HCV infection remains a significant concern in Asian hemodialysis patients, with a high overall prevalence.
  • Longer duration of hemodialysis and history of blood transfusion are identified as key risk factors.
  • Urgent need for enhanced preventive strategies and increased clinical attention to mitigate HCV transmission.
Abstract

More Related Videos

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

5.3K
A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

10.5K

Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
66
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
3.8K
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
1.0K
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
2.1K
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion...
15
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
383