Automatic assessment of tear film break-up dynamics

Dry eye syndrome is a common disorder of the tear film which affects a remarkable percentage of the population. The Break-Up Time (BUT) is a clinical test used for the diagnosis of this disease, which computes the time the first tear film break-up appears. This work describes a fully automatic methodology to compute the BUT measurement and evaluate the break-up dynamics until the final blink. This analysis provides useful additional information for the assessment of tear film stability.