Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

1.6K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.6K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.4K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.4K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

351
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
351
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

6.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
6.4K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

6.5K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
6.5K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

4.2K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PySpectro: A modular 3D printed, machine learning assisted optical device for recognition and quantification of samples.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2025
Same author

Gold leaf electrodes for UV/Vis spectroelectrochemical determination of ortho-diphenols in extra virgin olive oil.

Talanta·2024
Same author

Platelet Rich Plasma Therapy in Achilles and Patellar Tendinopathies: Outcomes in Subjects with Diabetes (A Retrospective Case-Control Study).

Journal of clinical medicine·2024
Same author

Epidemiology of Non-Contact Muscle Injuries in the Italian Male Elite Under-19 Football (Soccer) Championship.

Sports medicine - open·2024
Same author

Lab-on kit: A 3D printed portable device for optical and electrochemical dual-mode detection.

Talanta·2024
Same author

Musculoskeletal disorders in padel: from biomechanics to sonography.

Journal of ultrasound·2024

Related Experiment Video

Updated: Apr 19, 2026

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research
04:37

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research

Published on: March 1, 2024

1.5K

How obesity modifies tendons (implications for athletic activities).

Michele Abate1

  • 1Department of Medicine and Science of Aging, University "G. d'Annunzio" Chieti, Pescara, Italy.

Muscles, Ligaments and Tendons Journal
|December 10, 2014
PubMed
Summary
This summary is machine-generated.

Obesity can lead to tendon degeneration and pain due to chronic inflammation and altered tissue structure. While physical activity is beneficial, caution is needed to prevent injury in obese individuals with sub-clinical tendon damage.

Keywords:
obesitysporttendon

More Related Videos

Author Spotlight: Unraveling the Mechanobiology of Tendon Impingement – A Multiaxial Murine Hind Limb Explant Model
08:19

Author Spotlight: Unraveling the Mechanobiology of Tendon Impingement – A Multiaxial Murine Hind Limb Explant Model

Published on: December 8, 2023

1.7K
Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms
08:32

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms

Published on: March 22, 2024

2.0K

Related Experiment Videos

Last Updated: Apr 19, 2026

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research
04:37

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research

Published on: March 1, 2024

1.5K
Author Spotlight: Unraveling the Mechanobiology of Tendon Impingement – A Multiaxial Murine Hind Limb Explant Model
08:19

Author Spotlight: Unraveling the Mechanobiology of Tendon Impingement – A Multiaxial Murine Hind Limb Explant Model

Published on: December 8, 2023

1.7K
Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms
08:32

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms

Published on: March 22, 2024

2.0K

Area of Science:

  • Musculoskeletal disorders
  • Metabolic diseases
  • Cardiovascular diseases

Background:

  • Obesity is a significant risk factor for metabolic and cardiovascular diseases.
  • Obesity is increasingly associated with musculoskeletal disorders, particularly affecting tendons.

Purpose of the Study:

  • To investigate the relationship between obesity and tendon pathology.
  • To understand the pathogenetic mechanisms linking obesity to tendon degeneration.

Main Methods:

  • Systematic literature search using keywords: "obesity" or "body mass index" and "tendon" or "tendinopathy".
  • Analysis of English-language articles.

Main Results:

  • Obese individuals exhibit frequent tendon degeneration, leading to pain and functional impairment.
  • Histopathological findings include reduced collagen fibrils, impaired remodeling, lipid droplet deposition, and disorganized architecture.
  • Systemic factors from adipose tissue, such as inflammatory cytokines and hormones, contribute to tendon pathology.

Conclusions:

  • Physical activity is recommended for weight management in obese individuals.
  • Caution is advised during physical activity, as sub-clinical tendon damage can become symptomatic under overload.