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Infective endocarditis and complications; a single center experience
Olcay Ozveren1, Mehmet Akif Oztürk2, Cihan Sengül3
1Department of Cardiology, Yeditepe University Faculty of Medicine, İstanbul, Turkey.
Summary
Infective endocarditis (IE) remains a significant concern, often presenting with fever and malaise. Staphylococcus aureus was a common cause in culture-positive cases, highlighting the need for effective management strategies.
Area of Science:
- Cardiology
- Infectious Diseases
- Microbiology
Background:
- Infective endocarditis (IE) poses a substantial clinical challenge.
- Understanding IE's microbiological profile and complications is crucial for patient outcomes.
Purpose of the Study:
- To investigate the microbiological characteristics of infective endocarditis (IE).
- To identify common complications associated with IE in a patient cohort.
- To analyze clinical and microbiological properties of IE patients.
Main Methods:
- Retrospective review of 119 patients diagnosed with IE between 1997 and 2004.
- Diagnosis confirmed using modified Duke criteria.
- Systematic analysis of clinical data, microbiological findings, and complications.
Main Results:
- Fever and malaise were the most frequent symptoms (85.7%).
- Blood cultures were negative in 57.1% of cases; Staphylococcus aureus was the most common pathogen in positive cultures.
- The aortic valve was the most affected site (36.1%); high rates of surgical intervention (75.6%) and congestive heart failure (53.8%) were observed.
Conclusions:
- Infective endocarditis (IE) continues to be a serious disease with significant morbidity and mortality.
- Increased life expectancy and valve replacement procedures underscore the persistent impact of IE.
- Further research into IE's microbiological agents and management is warranted.
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