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Infective endocarditis and complications; a single center experience

Olcay Ozveren1, Mehmet Akif Oztürk2, Cihan Sengül3

  • 1Department of Cardiology, Yeditepe University Faculty of Medicine, İstanbul, Turkey.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|December 10, 2014
PubMed

Insights

Infective endocarditis (IE) remains a significant concern, often presenting with fever and malaise. Staphylococcus aureus was a common cause in culture-positive cases, highlighting the need for effective management strategies.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Microbiology

Background:

  • Infective endocarditis (IE) poses a substantial clinical challenge.
  • Understanding IE's microbiological profile and complications is crucial for patient outcomes.

Purpose of the Study:

  • To investigate the microbiological characteristics of infective endocarditis (IE).
  • To identify common complications associated with IE in a patient cohort.
  • To analyze clinical and microbiological properties of IE patients.

Main Methods:

  • Retrospective review of 119 patients diagnosed with IE between 1997 and 2004.
  • Diagnosis confirmed using modified Duke criteria.
  • Systematic analysis of clinical data, microbiological findings, and complications.

Main Results:

  • Fever and malaise were the most frequent symptoms (85.7%).
  • Blood cultures were negative in 57.1% of cases; Staphylococcus aureus was the most common pathogen in positive cultures.
  • The aortic valve was the most affected site (36.1%); high rates of surgical intervention (75.6%) and congestive heart failure (53.8%) were observed.

Conclusions:

  • Infective endocarditis (IE) continues to be a serious disease with significant morbidity and mortality.
  • Increased life expectancy and valve replacement procedures underscore the persistent impact of IE.
  • Further research into IE's microbiological agents and management is warranted.
Abstract

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