Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The second-messenger system for peptide hormones.

R M Hanley1, A L Steiner

  • 1Department of Medicine, University of Texas Medical School, Houston.

Hospital Practice (Office Ed.)
|August 15, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The cost-effectiveness of treating women with a cervical vaginal smear diagnosis of atypical squamous cells of undetermined significance.

American journal of obstetrics and gynecology·1998
Same author

Cytochrome c mRNA levels decrease in senescent rat heart.

Mechanisms of ageing and development·1991
Same author

Problems encountered with the Bethesda System: the University of Iowa experience.

Obstetrics and gynecology·1991
Same author

The effect of phorbol esters on the expression of mRNA for the alpha subunit of calcium/calmodulin dependent protein kinase II in rabbit renal proximal tubules.

Second messengers and phosphoproteins·1991
Same author

'Diabetic' emergencies. They happen with or without diabetes.

Postgraduate medicine·1990
Same author

Identification of calcium-calmodulin multifunctional protein kinase II in rabbit kidney.

Kidney international·1990
Same journal

Oral contraceptives: an update.

Hospital practice (Office ed.)·1995
Same journal

Progress in the immunogenetics of rheumatoid arthritis.

Hospital practice (Office ed.)·1995
Same journal

An asymptomatic lung nodule in an elderly woman with joint pain.

Hospital practice (Office ed.)·1995
Same journal

Defusing status epilepticus.

Hospital practice (Office ed.)·1995
Same journal

Persistent fever and flank discomfort in a young woman.

Hospital practice (Office ed.)·1995
Same journal

New thoughts on attention-deficit/hyperactivity disorder.

Hospital practice (Office ed.)·1995
See all related articles

Peptide hormones use G protein signaling pathways for cell communication. Redundant second messengers ensure precise cellular regulation, maintaining biological balance.

Area of Science:

  • Cellular biology
  • Endocrinology
  • Molecular signaling

Background:

  • Hormones regulate cellular functions through diverse signaling mechanisms.
  • Three major classes exist: peptide, steroid, and growth factors.
  • Signal transduction pathways are crucial for cellular response and regulation.

Purpose of the Study:

  • To propose two key theses regarding peptide hormone signal transduction.
  • To elucidate the role of G proteins in peptide hormone signaling.
  • To explore the significance of second-messenger redundancy in cell regulation.

Main Methods:

  • The study is theoretical, proposing hypotheses based on existing knowledge.
  • It focuses on the mechanisms of signal transduction for peptide hormones.

Related Experiment Videos

  • Analysis involves understanding G protein coupling and second-messenger pathways.

    • Main Results:

    • Incoming peptide hormone signals necessitate coupling to G proteins.
    • Signal transduction occurs via a second-messenger pathway.
    • Second-messenger redundancy provides regulatory checks and balances.

    Conclusions:

    • Peptide hormone signaling relies on G protein-mediated, second-messenger pathways.
    • Redundancy in second messengers is essential for robust cell regulation.
    • These mechanisms ensure precise control over cellular processes.