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Updated: Apr 19, 2026

Purification and Visualization of Lipopolysaccharide from Gram-negative Bacteria by Hot Aqueous-phenol Extraction
Published on: May 28, 2012
(Lipo)polysaccharide interactions of antimicrobial peptides
Artur Schmidtchen1, Martin Malmsten2
1Section of Dermatology and Venereology, Department of Clinical Sciences, Lund University, SE-221 84 Lund, Sweden; Dermatology, LKCMedicine, Nanyang Technological University, Singapore 308232, Singapore.
Abstract:
Due to rapidly increasing resistance development against conventional antibiotics, as well as problems associated with diseases either triggered or deteriorated by infection, antimicrobial and anti-inflammatory peptides have attracted considerable interest during the last few years. While there is an emerging understanding of the direct antimicrobial function of such peptides through bacterial membrane destabilization, the mechanisms of their anti-inflammatory function are less clear. We here summarize some recent results obtained from our own research on anti-inflammatory peptides, with focus on peptide-(lipo)polysaccharide interactions.
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