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Enhancement of peripheral nerve regeneration by pharmacological activation of the cyclic AMP second messenger system
H W Klein1, S Kilmer, R C Carlsen
1Department of Surgery, University of California School of Medicine, Davis.
Microsurgery
|January 1, 1989
Abstract:
This paper reviews the history of attempts to study peripheral nerve regeneration, focusing upon pharmacologic agents that may prove to be useful clinically. In particular, forskolin is described as a model for such an agent, and its mechanism of action, as a stimulator of the cyclic AMP second messenger system, is described.