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Specific immunoglobulin response in mice immunized with porins and challenged with Salmonella typhi
P Sharma1, N K Ganguly, B K Sharma
1Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Microbiology and Immunology
|January 1, 1989
Abstract:
Specific antiporin antibody (IgG, IgM, and IgA) response was studied in control, infected, immunized-infected, and immunized mice. The activity of specific IgG immunoglobulins was found to be the highest in immunized and immunized-infected groups in which 87.5% protection had been observed by laboratory potency test in mice; the next-highest activities were those of IgM and IgA immunoglobulins. However, in the infected group the activity of specific IgM and IgG immunoglobulins was almost similar.