[Genetic counseling for individuals with hemoglobin disorders and for their relatives: a systematic literature review]
Related Experiment Video
Updated: Apr 19, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Tatiana Dela-Sávia Ferreira1, Elisângela de Paula Silveira-Lacerda2, Marco Tulio Antonio García-Zapata3
1Federal University of Goiás, Goiânia, GO, Brazil.
Objective:
To identify genetic counseling programs that do not encourage therapeutic abortion for individuals with hemoglobin disorders and/or for their relatives.
Method:
Systematic literature review of articles published from 2001 to 2012 that are located in the PubMed, LILACS, SciELO and SCOPUS databases using keywords in Portuguese, English and Spanish and that met the inclusion and exclusion criteria described on a standardized form.
Results:
A total of 409 articles were located, but only eight (1.9%) were selected for analysis.
Conclusion:
Although seldom mentioned in the literature, educational/preventive programs targeting hemoglobinopathies are feasible and allow the affected individuals to acquire knowledge on the consequences of this condition and their odds of transmitting it.
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