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Updated: Apr 19, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
The optimization of superficial planning target volumes (PTVs) with helical tomotherapy
Mark J Ashburner1, Samuel Tudor
1Addenbrooke's Hospital Cambridge. mark.ashburner@waikatodhb.health.nz.
Abstract:
When the planning target volume (PTV), extends close to or beyond the skin, inverse-planned intensity-modulated radiotherapy can boost the fluence from tan- gential angles to superficial parts of the PTV due to the buildup effect. This can result in significant regions of high dose upon a small movement in the patient's position. We analyzed different methods of reducing this effect in the TomoTherapy planning system, including using pretend bolus, clipping the PTV back from the skin surface, and combinations of both. No alternative technique was seen to be unconditionally superior to a 5 mm planning bolus. A clip distance of 3 mm gave acceptable results, but consideration should be given to the reduction in minimum dose or increase in maximum dose seen in clip distances just 1 mm less or more, respectively, when treating head and neck cases in TomoTherapy.

