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Histology of the Small Intestine01:27

Histology of the Small Intestine

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The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
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Related Experiment Video

Updated: Apr 19, 2026

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine
08:00

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine

Published on: June 24, 2019

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Primary Intestinal Lymphoma: A Clinicopathological Study.

P J Yaranal1, S G Harish, B Purushotham

  • 1Department of Pathology, Kannur Medical College, India.

Indian Journal of Cancer
|December 11, 2014
PubMed
Summary

Primary intestinal lymphoma (PIL) is a rare extranodal lymphoma. This study found that non-Hodgkin

Area of Science:

  • Gastroenterology
  • Oncology
  • Hematology

Background:

  • Primary intestinal lymphoma (PIL) is an extranodal lymphoma originating in the intestine.
  • This study focuses on primary non-Hodgkin's lymphoma (NHL) of the small and large intestine.

Purpose of the Study:

  • To evaluate the clinicopathological characteristics of primary intestinal non-Hodgkin's lymphoma (NHL).
  • Reclassify cases according to the 2001 World Health Organization classification of lymphoma.
  • Utilize immunohistochemistry (IHC) for accurate histopathological diagnosis.

Main Methods:

  • Retrospective analysis of 11 primary intestinal non-Hodgkin's lymphoma (NHL) cases over 5 years.
  • Inclusion of both resected intestinal specimens and biopsy specimens.
  • Histopathological examination using light microscopy and immunohistochemistry (CD5, 20, 21, cyclin D1).

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Isolating Lymphocytes from the Mouse Small Intestinal Immune System
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Last Updated: Apr 19, 2026

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Isolating Lymphocytes from the Mouse Small Intestinal Immune System
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Main Results:

  • Abdominal pain and lump were common presenting symptoms.
  • NHLS were more prevalent in the small intestine, predominantly affecting adults (75% >46 years) with a male predominance.
  • The majority of cases were B-cell type NHL, including diffuse large B-cell lymphoma, mucosa-associated lymphatic tissue lymphoma, and follicular lymphoma.

Conclusions:

  • Primary intestinal lymphomas (PILs) are rare and distinct from gastric lymphomas in pathology, clinical features, management, and prognosis.
  • Due to non-specific symptoms and low incidence, PILs are often misdiagnosed until complications arise.
  • Accurate and timely diagnosis of PIL is crucial to prevent severe complications like perforation and bleeding.