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The association between breastfeeding and childhood obesity: a meta-analysis
1Division of Community Health and Humanities, Faculty of Medicine, Memorial University of Newfoundland, St, John's, Newfoundland and Labrador A1B 3 V6, Canada. huangguowei@tmu.edu.cn.
Insights
Breastfeeding significantly lowers the risk of childhood obesity, according to a meta-analysis. This protective effect shows a dose-response relationship with breastfeeding duration, highlighting its public health importance.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Childhood obesity presents a significant public health challenge.
- Evidence on the link between breastfeeding and reduced childhood obesity risk is conflicting.
- This meta-analysis aimed to clarify the association between breastfeeding and childhood obesity risk.
Purpose of the Study:
- To conduct a meta-analysis investigating the association between breastfeeding and the risk of childhood obesity.
- To synthesize evidence from multiple studies to provide a robust conclusion on this relationship.
Main Methods:
- Systematic literature search of PubMed, EMBASE, and CINAHL Plus databases up to August 1, 2014.
- Pooled adjusted odds ratio (AOR) and 95% confidence interval (CI) calculated for meta-analysis.
- Heterogeneity assessed using I2 statistic; publication bias evaluated using funnel plots and Fail-safe N, with Egger and Begg tests reported.
Main Results:
- Included 25 studies with 226,508 participants, published between 1997 and 2014, across 12 countries.
- Breastfeeding was associated with a significantly reduced risk of childhood obesity (AOR = 0.78; 95% CI: 0.74, 0.81).
- Analysis of 17 studies indicated a dose-response effect, where longer breastfeeding duration correlated with a lower obesity risk.
Conclusions:
- Breastfeeding is a significant protective factor against childhood obesity.
- The findings support breastfeeding as a key strategy in preventing childhood obesity.
Background:
The increase in childhood obesity is a serious public health concern. Several studies have indicated that breastfed children have a lower risk of childhood obesity than those who were not breastfed, while other studies have provided conflicting evidence. The objective of this meta-analysis was to investigate the association between breastfeeding and the risk of childhood obesity.
Methods:
The PubMed, EMBASE and CINAHL Plus with Full Text databases were systematically searched from start date to 1st August 2014. Based on the meta-analysis, pooled adjusted odds ratio (AOR) and 95% confidence interval (CI) were calculated. I2 statistic was used to evaluate the between-study heterogeneity. Funnel plots and Fail-safe N were used to assess publication bias and reliability of results, and results from both Egger test and Begg test were reported.
Results:
Twenty-five studies with a total of 226,508 participants were included in this meta-analysis. The studies' publication dates ranged from 1997 to 2014, and they examined the population of 12 countries. Results showed that breastfeeding was associated with a significantly reduced risk of obesity in children (AOR = 0.78; 95% CI: 0.74, 0.81). Categorical analysis of 17 studies revealed a dose-response effect between breastfeeding duration and reduced risk of childhood obesity.
Conclusion:
Results of our meta-analysis suggest that breastfeeding is a significant protective factor against obesity in children.
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