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Updated: Apr 19, 2026

Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
Implementation of an error-reporting module within a biorepository IT application to enhance operations.
Kerry R Wiles1, M K Washington
1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center , CHTN Western Division, Nashville, Tennessee.
The Collaborative Human Tissue Network (CHTN) Western Division improved biospecimen resource sustainability by implementing an IT-based error-reporting module. This innovation streamlined operations and enhanced performance tracking in a challenging funding environment.
Area of Science:
- Biorepository operations
- Biospecimen resource management
- Health services research
Background:
- Federally funded biospecimen networks face sustainability challenges due to funding constraints.
- Operational efficiency is crucial for providing high-quality biospecimens to researchers.
- The Collaborative Human Tissue Network (CHTN) aims to support basic research through accessible biospecimens.
Purpose of the Study:
- To enhance the sustainability of biospecimen resources within the CHTN Western Division.
- To address operational inefficiencies through process innovation and IT solutions.
- To improve the reporting and analysis of operational progress and performance issues.
Main Methods:
- Implementation of a Lean Six Sigma (LSS) methodology to identify inefficiencies.
- Redesign of workflows and processes using IT enhancements.
- Development and integration of an error-reporting module (ERM) within the biorepository IT application.
Main Results:
- The ERM allows immediate error reporting, identification of responsible areas, and severity assessment.
- Automated alerts notify relevant personnel, facilitating timely resolution.
- The module provides data-reporting features for management analysis of operational performance.
Conclusions:
- IT-driven process innovation, exemplified by the ERM, is vital for biospecimen resource sustainability.
- Lean Six Sigma principles can effectively identify and address operational inefficiencies.
- Enhanced data reporting improves oversight and strategic decision-making in biorepository management.
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