Related Experiment Video
Updated: Apr 19, 2026
Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
Birth weight is associated with inner cell mass grade of blastocysts
Frederick Licciardi1, Caroline McCaffrey1, Cheongeun Oh1
1New York University Fertility Center, New York University Langone Medical Center, New York, New York.
Objective:
To determine the relationship between blastocyst growth parameters and birth weight.
Design:
Cohort study.
Setting:
University-affiliated fertility center.
Patient(S):
In vitro patients who delivered a singleton after a single-blastocyst transfer.
Intervention(S):
None.
Main Outcome Measure(S):
Birth weight adjusted for gestational age at delivery and gender, with adjusted birth weight examined for association with blastocyst scores and grades.
Result(S):
After standard in vitro fertilization (IVF) and thawed embryo transfers, greater birth weight was associated with a higher inner cell mass grade. The grade of the trophectoderm and stage of the blastocyst did not relate to weight.
Conclusion(S):
Embryonic growth as early as day 5 can predict the progress of fetal development as measured by birth weight.
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