First reported case of sextuplets conceived via letrozole for ovulation induction
Gunwant Warraich1, Tannys D R Vause1
1Ottawa Fertility Centre, Ottawa, Ontario, Canada.
Objective:
To report the first case of sextuplets conceived via letrozole during ovulation induction.
Design:
Case report.
Setting:
Private fertility clinic.
Patient(S):
A 32-year-old female with a history of secondary infertility and polycystic ovary syndrome.
Intervention(S):
Letrozole, 7.5 mg, on cycle days 3-7 after a progesterone-induced menses.
Main Outcome Measure(S):
Clinical pregnancy.
Result(S):
Sexchorionic-sexamniotic pregnancy.
Conclusion(S):
High-order multiple gestations are possible with letrozole ovulation induction, so patients should be counseled appropriately and follicle monitoring considered.
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