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Updated: Apr 19, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
Published on: September 11, 2018
[Effects of smoking on venous cannulation pain: a randomized prospective trial]
Volkan Hanci1, Hasan Ali Kiraz2, Dilek Omür1
1Departamento de Anestesiologia e Reanimação, Dokuz Eylul University Medical Faculty, Konak, Turquia.
Background And Objectives:
It has been demonstrated that smoking increases pain perception; however the effect of smoking on perception of pain during venous cannulation is not known. The purpose of this study is to determine whether or not smoking has an effect on pain perception due to peripheral venous cannulation.
Methods:
220 patients scheduled to have elective surgery were enrolled in the study and were divided into two groups (Group S and C, n=110 for each) according to their smoking habits. Numerical rating scale was introduced to the patients and then peripheral venous cannulation at the dorsum of the hand was made with a 20G intracath. Pain perception of the patients was scored by subsequent numerical rating scale questioning.
Results:
The demographic characteristics of the groups were identical. Numerical rating scale scores in Group S and C were 3.31±1.56 and 1.65±1.23, respectively (p<0.001).
Conclusion:
Pain perception due to peripheral venous cannulation is higher in smokers. Future studies on pain treatment should consider the smoking habits of patients.
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