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Dopamine D3 receptor agonists as pharmacological tools

S Kassel1, J S Schwed1, H Stark1

  • 1Heinrich-Heine-University, Universitaetsstr. 1, 40225 Duesseldorf, Germany.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
|December 16, 2014
PubMed
Summary

This review details dopamine D3 receptor agonists, classifying ergoline and non-ergoline compounds. It examines their pharmacodynamics, species differences, and signaling mechanisms to aid in selecting optimal drug candidates for neurological disorders.

Keywords:
AffinityDopamine D(3) receptorEfficacyGPCRPharmacophoreSelectivity

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