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Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
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Brain development in ADHD.

Lisa A Friedman1, Judith L Rapoport1

  • 1Child Psychiatry Branch, National Institutes of Mental Health, National Institutes of Health, Bethesda, MD, United States.

Current Opinion in Neurobiology
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Summary
This summary is machine-generated.

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder influenced by genetics and brain differences. Treatment with psychostimulants can normalize brain structure and function in individuals with ADHD.

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Area of Science:

  • Neuropsychiatry
  • Developmental Neuroscience
  • Neuroimaging

Background:

  • Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder.
  • Genetic and familial factors are significant in ADHD etiology.
  • Brain anatomical and functional measures are key research areas.

Purpose of the Study:

  • To investigate brain anatomical and functional measures in ADHD.
  • To explore the developmental course of ADHD using longitudinal studies.
  • To compare persisting and remitting ADHD cases.

Main Methods:

  • Utilized advanced neuroimaging technologies to identify brain differences.
  • Conducted longitudinal studies to track developmental trajectories.
  • Compared individuals with and without ADHD, as well as persisting and remitting cases.

Main Results:

  • Neuroimaging revealed structural and functional brain differences in individuals with ADHD.
  • Longitudinal data provided insights into the developmental course of ADHD.
  • Psychostimulant medication at therapeutic doses demonstrated a normalizing effect on brain measures.

Conclusions:

  • ADHD is characterized by distinct neurobiological underpinnings.
  • Developmental trajectories and genetic factors play crucial roles in ADHD.
  • Psychostimulant treatment can positively impact brain anatomy and function in ADHD.