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An electrical cause of stridor: pediatric vagal nerve stimulators
Gregory Kelts1, Peter D O'Connor2, Richard W Hussey3
1San Antonio Uniformed Services Health Education Consortium, Otolaryngology, United States.
Insights
Vagal nerve stimulators (VNS) can cause breathing issues like stridor and sleep apnea in children with epilepsy. Adjusting VNS device settings resolved these adverse effects, improving patient outcomes.
Area of Science:
- Pediatric Otolaryngology
- Neurology
- Medical Device Engineering
Background:
- Vagal nerve stimulators (VNS) are FDA-approved implantable devices for treating refractory epilepsy in children.
- Potential side effects of VNS implantation require careful monitoring and management.
Observation:
- Two pediatric patients with epilepsy developed stridor and sleep apnea post-VNS implantation.
- Clinical evaluation included flexible laryngoscopy, direct laryngoscopy, and bronchoscopy.
Findings:
- Vocal fold and supraglottis contraction was observed in both patients.
- Adjusting VNS device parameters successfully eliminated these contractions.
Implications:
- VNS device settings may need optimization to prevent or treat airway complications.
- This highlights the importance of multidisciplinary care in managing VNS therapy side effects.
Abstract:
Vagal nerve stimulators (VNS) are surgically implantable medical devices which are approved by the food and drug administration (FDA) for treatment of medically refractory epilepsy in children. Two children with seizures disorders presented to the pediatric otolaryngology clinic with complaints of stridor and sleep apnea following implantation of VNS devices. Both children were evaluated with flexible laryngoscopy, direct laryngoscopy and bronchoscopy. The children were noted to have contraction of their vocal folds and supraglottis and the settings of their VNS were adjusted until no further contractions were noted. Each child had resolution of their symptoms following adjustment.
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