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Related Experiment Video

Updated: Apr 19, 2026

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications

Published on: May 10, 2024

Negative pressure wound therapy for partial-thickness burns.

Jo C Dumville¹, Christopher Munson, Janice Christie

¹School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, M13 9PL, UK. jo.dumville@manchester.ac.uk

The Cochrane Database of Systematic Reviews

|December 16, 2014

Summary

Negative pressure wound therapy (NPWT) is a newer strategy for burn wound treatment. However, current evidence is insufficient to conclude its effectiveness for partial-thickness burns.

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Area of Science:

Wound healing research
Clinical trial analysis
Burn management strategies

Background:

Burn wounds present complex local and systemic challenges.
Standard treatments include dressings and advanced therapies like negative pressure wound therapy (NPWT).
NPWT utilizes suction to drain excess fluid, aiming to enhance healing and minimize burn progression.

Purpose of the Study:

To evaluate the efficacy of NPWT in treating partial-thickness burns.
To synthesize evidence from randomized controlled trials (RCTs) and controlled clinical trials (CCTs).

Main Methods:

Searched Cochrane Wounds Group Specialised Register and CENTRAL up to September 2014.
Included RCTs and CCTs assessing NPWT for partial-thickness burns.
Independent data extraction and risk of bias assessment by two reviewers.

Main Results:

Only one interim RCT met inclusion criteria.
A narrative synthesis was performed due to lack of data and poor reporting.
The included trial had a high risk of bias, precluding statistical analysis.

Conclusions:

Insufficient evidence exists to draw conclusions on NPWT for partial-thickness burn wounds.
Further high-quality research is needed to determine NPWT's role in burn care.